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Microsomal prostaglandin E synthetase-1 gene (mPGES-1) and the PGE2 produced in the spleen are the key factors connecting the immune and nervous systems affected by nicotine (Revathikumar et al., 2018)

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My idea is that when we target the frontopolar area, we are modulating those subcortical areas in a beneficial way, Ekhtiari says

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